rs5848(C;C)

Lower dementia risk

Magnitude
3.0Important
Repute
Good
Frequency
38%Average of 11 populations
On SNPedia
rs5848(G;G)Minus strand
Gene
GRN

Frequency

Share of people with C;C in each HapMap population.

  • Mexican ancestry (Los Angeles)60%
  • European ancestry (Utah)57%
  • Gujarati Indian55%
  • Japanese (Tokyo)52%
  • Tuscan48%
  • Han Chinese (Beijing)43%
  • Chinese (Denver)39%
  • Maasai (Kenya)34%
  • African ancestry (Southwest US)14%
  • Luhya (Kenya)12%
  • Yoruba (Nigeria)3%

Other genotypes of rs5848

  1. T;TMost notableBadSomewhat increased (~2 - 3x) dementia riskImportant · 3.019% of people
  2. C;TBadSomewhat increased (~2 - 3x) dementia riskWorth knowing · 2.043% of people

All about rs5848

Notes

From SNPedia

Lower risk of frontotemporal dementia, alzheimer's disease and parkinson's disease.

Source and license

Adapted from rs5848(G;G) on SNPedia, using a snapshot taken October 16, 2026. SNPedia content is shared under CC BY-NC-SA 3.0 US, and this page is shared under the same license.

SNPedia is a community-edited wiki. Its entries can be incomplete, out of date or wrong, and nothing here is a diagnosis or medical advice. Magnitude is a community rating of how interesting a genotype is, not a risk score.