rs5848(C;T)

Somewhat increased (~2 - 3x) dementia risk

Magnitude
2.0Worth knowing
Repute
Bad
Frequency
43%Average of 11 populations
On SNPedia
rs5848(A;G)Minus strand
Gene
GRN

Frequency

Share of people with C;T in each HapMap population.

  • Luhya (Kenya)52%
  • African ancestry (Southwest US)51%
  • Chinese (Denver)47%
  • Tuscan47%
  • Maasai (Kenya)46%
  • Han Chinese (Beijing)44%
  • Japanese (Tokyo)43%
  • European ancestry (Utah)39%
  • Yoruba (Nigeria)37%
  • Gujarati Indian36%
  • Mexican ancestry (Los Angeles)33%

Other genotypes of rs5848

  1. T;TMost notableBadSomewhat increased (~2 - 3x) dementia riskImportant · 3.019% of people
  2. C;CGoodlower dementia riskImportant · 3.038% of people

All about rs5848

Notes

From SNPedia

Somewhat increased risk of frontotemporal dementia, alzheimer's disease and parkinson's disease; see discussion at rs5848.

Source and license

Adapted from rs5848(A;G) on SNPedia, using a snapshot taken October 16, 2026. SNPedia content is shared under CC BY-NC-SA 3.0 US, and this page is shared under the same license.

SNPedia is a community-edited wiki. Its entries can be incomplete, out of date or wrong, and nothing here is a diagnosis or medical advice. Magnitude is a community rating of how interesting a genotype is, not a risk score.