rs5848(T;T)

Somewhat increased (~2 - 3x) dementia risk

Magnitude
3.0Important
Repute
Bad
Frequency
19%Average of 11 populations
On SNPedia
rs5848(A;A)Minus strand
Gene
GRN

Frequency

Share of people with T;T in each HapMap population.

  • Yoruba (Nigeria)60%
  • Luhya (Kenya)36%
  • African ancestry (Southwest US)35%
  • Maasai (Kenya)20%
  • Chinese (Denver)15%
  • Han Chinese (Beijing)13%
  • Gujarati Indian9%
  • Mexican ancestry (Los Angeles)7%
  • Tuscan6%
  • Japanese (Tokyo)5%
  • European ancestry (Utah)4%

Other genotypes of rs5848

  1. C;TBadSomewhat increased (~2 - 3x) dementia riskWorth knowing · 2.043% of people
  2. C;CGoodlower dementia riskImportant · 3.038% of people

All about rs5848

Notes

From SNPedia

Somewhat increased risk of Fronto-Temporal Dementia and Parkinsons disease; see discussion at rs5848

Source and license

Adapted from rs5848(A;A) on SNPedia, using a snapshot taken October 16, 2026. SNPedia content is shared under CC BY-NC-SA 3.0 US, and this page is shared under the same license.

SNPedia is a community-edited wiki. Its entries can be incomplete, out of date or wrong, and nothing here is a diagnosis or medical advice. Magnitude is a community rating of how interesting a genotype is, not a risk score.