rs587776573
A SNP in the WT1 gene on chromosome 11. Its most notable genotype is -;ATTTATACCAAATGACA: Wilms tumor susceptibility (predicted)
- Gene
- WT1
- Location
- Chr 1132,417,633 (GRCh38)
- Highest magnitude
- 7.5Very important
- Tested on
- AncestryDNA
Genotypes
As shown in 23andMe and AncestryDNA files.
- -;ATTTATACCAAATGACAMost notableBadWilms tumor susceptibility (predicted)
- -;TGTCATTTGGTATAAATBadWilms tumor susceptibility (predicted)
- ATTTATACCAAATGACA;ATTTATACCAAATGACAGoodcommon in clinvar
- ATTTATACCAAATGACAT;ATTTATACCAAATGACATGoodcommon in clinvar
- TGTCATTTGGTATAAAT;TGTCATTTGGTATAAATGoodcommon in clinvar
On SNPedia: (-;ATTTATACCAAATGACA), (-;TGTCATTTGGTATAAAT), (ATTTATACCAAATGACA;ATTTATACCAAATGACA), (ATTTATACCAAATGACAT;ATTTATACCAAATGACAT), (TGTCATTTGGTATAAAT;TGTCATTTGGTATAAAT). Magnitude rates how notable a genotype is from 0 to 10, not how risky it is.
Related
Other WT1 SNPs
- rs28941778C;TDenys-Drash syndromeVery important
- rs28941779A;GFrasier syndrome mutationVery important
- rs28942089A;GDenys-Drash syndromeVery important
- rs121907900A;GWilms tumor susceptibility (predicted)Very important
- rs121907906A;GWilms tumor susceptibility (predicted)Very important
- rs121907908C;TWilms tumor susceptibility (predicted)Very important
- rs121907909A;GWilms tumor susceptibility (predicted)Very important
- rs121907911G;TWilms tumor susceptibility (predicted)Very important
Notes
From SNPedia
Notes
aka c.242_258del17 (p.Asn81Ilefs)
Source and license
Adapted from rs587776573 on SNPedia, using a snapshot taken October 16, 2026. SNPedia content is shared under CC BY-NC-SA 3.0 US, and this page is shared under the same license.
SNPedia is a community-edited wiki. Its entries can be incomplete, out of date or wrong, and nothing here is a diagnosis or medical advice. Magnitude is a community rating of how interesting a genotype is, not a risk score.