rs5882(A;G)

Lower risk of dementia and Alzheimer's disease. Higher good cholesterol.

Magnitude
2.0Worth knowing
Repute
Good
Frequency
47%Average of 11 populations
On SNPedia
rs5882(A;G)
Gene
CETP

Frequency

Share of people with A;G in each HapMap population.

  • African ancestry (Southwest US)54%
  • Mexican ancestry (Los Angeles)52%
  • Chinese (Denver)51%
  • Gujarati Indian51%
  • Han Chinese (Beijing)47%
  • Japanese (Tokyo)47%
  • Luhya (Kenya)46%
  • Yoruba (Nigeria)44%
  • Maasai (Kenya)44%
  • Tuscan41%
  • European ancestry (Utah)40%

Other genotypes of rs5882

  1. A;ABadFaster aging. Increased risk for Dementia. Less good cholesterol.Worth knowing · 2.027% of people
  2. G;GMost notableGoodLonger lifespan, 0.28x lower risk of dementia, 0.31x lower risk of Alzheimer's.Worth knowing · 2.126% of people

All about rs5882

Notes

From SNPedia

One copy of a longevity gene. This seems to raise HDL ("good") cholesterol, and reduce the risk of dementia and Alzheimer's disease. It may slightly increase longevity. It has been particularly studied in Ashkenazi Jews.

Source and license

Adapted from rs5882(A;G) on SNPedia, using a snapshot taken October 16, 2026. SNPedia content is shared under CC BY-NC-SA 3.0 US, and this page is shared under the same license.

SNPedia is a community-edited wiki. Its entries can be incomplete, out of date or wrong, and nothing here is a diagnosis or medical advice. Magnitude is a community rating of how interesting a genotype is, not a risk score.