rs6350
A SNP in the SLC6A3 gene on chromosome 5. Its most notable genotype is G;G.
- Gene
- SLC6A3
- Location
- Chr 51,443,084 (GRCh38)
- Highest magnitude
- 0.0Typical
- Tested on
- 23andMe, AncestryDNA, FamilyTreeDNA
- Minor allele frequency
- 5%
Genotypes
Plus strand, as in 23andMe and AncestryDNA files.
SNPedia records rs6350 on the minus strand: (C;C). Magnitude rates how notable a genotype is from 0 to 10, not how risky it is.
Frequency
Share of each genotype in 11 HapMap populations.
- AverageG;G 91%
- European ancestry (Utah)G;G 85%
- Han Chinese (Beijing)G;G 98%
- Japanese (Tokyo)G;G 97%
- Yoruba (Nigeria)G;G 94%
- African ancestry (Southwest US)G;G 97%
- Chinese (Denver)G;G 99%
- Gujarati IndianG;G 91%
- Luhya (Kenya)G;G 86%
- Mexican ancestry (Los Angeles)G;G 91%
- Maasai (Kenya)G;G 83%
- TuscanG;G 81%
Related
Other SLC6A3 SNPs
- rs267607068T;TInfantile Parkinsonism-dystoniaVery important
- rs267607069A;AInfantile Parkinsonism-dystoniaVery important
- rs431905504T;TInfantile Parkinsonism-dystoniaVery important
- rs431905514T;TInfantile Parkinsonism-dystoniaVery important
- rs431905515G;GInfantile Parkinsonism-dystoniaVery important
- rs431905516A;AInfantile Parkinsonism-dystoniaVery important
- rs27072C;C2x risk of severe alcohol withdrawal. Possible increased odds of ADHD.Worth knowing
- rs460000G;GBetter response to amphetamineWorth knowing
Notes
From SNPedia
Notes
Genetic polymorphisms in monoamine neurotransmitter systems show only weak association with acute post-surgical pain in humans. SLC6A3 and body mass index in the Prostate, Lung, Colorectal and Ovarian Cancer Screening Trial. Familiality and molecular genetics of attention networks in ADHD. Financial and psychological risk attitudes associated with two single nucleotide polymorphisms in the nicotine receptor (CHRNA4) gene.
Source and license
Adapted from rs6350 on SNPedia, using a snapshot taken October 16, 2026. SNPedia content is shared under CC BY-NC-SA 3.0 US, and this page is shared under the same license.
SNPedia is a community-edited wiki. Its entries can be incomplete, out of date or wrong, and nothing here is a diagnosis or medical advice. Magnitude is a community rating of how interesting a genotype is, not a risk score.