rs6413419

A SNP in the CYP2E1 gene on chromosome 10. Its most notable genotype is A;A: CYP2E1*4 homozygote

Gene
CYP2E1
Location
Chr 10133,532,171 (GRCh38)
Highest magnitude
0.0Typical
Tested on
23andMe, AncestryDNA, FamilyTreeDNA
Minor allele frequency
7%

Genotypes

As shown in 23andMe and AncestryDNA files.

  1. A;AMost notableNot ratedCYP2E1*4 homozygoteTypical · 0.01% of people
  2. A;GNot ratedcarrier of one CYP2E1*4 alleleTypical · 0.015% of people
  3. G;GGoodnormalTypical · 0.084% of people

On SNPedia: (A;A), (A;G), (G;G). Magnitude rates how notable a genotype is from 0 to 10, not how risky it is.

Frequency

Share of each genotype in 10 HapMap populations.

  • AverageA;A 1% A;G 15% G;G 84%
  • European ancestry (Utah)A;A 0% A;G 4% G;G 96%
  • Han Chinese (Beijing)A;A 0% A;G 0% G;G 100%
  • Japanese (Tokyo)A;A 0% A;G 0% G;G 100%
  • Yoruba (Nigeria)A;A 8% A;G 44% G;G 48%
  • African ancestry (Southwest US)A;A 4% A;G 39% G;G 58%
  • Gujarati IndianA;A 0% A;G 2% G;G 98%
  • Luhya (Kenya)A;A <1% A;G 29% G;G 70%
  • Mexican ancestry (Los Angeles)A;A 0% A;G 9% G;G 91%
  • Maasai (Kenya)A;A 0% A;G 16% G;G 84%
  • TuscanA;A 0% A;G 8% G;G 92%

Other CYP2E1 SNPs

All CYP2E1 SNPs

Notes

From SNPedia

Notes

rs6413419, also known as 4768G>A or V179I, is a SNP in the CYP2E1 gene. The rs6413419(A) allele defines the CYP2E1*4 variant.

Source and license

Adapted from rs6413419 on SNPedia, using a snapshot taken October 16, 2026. SNPedia content is shared under CC BY-NC-SA 3.0 US, and this page is shared under the same license.

SNPedia is a community-edited wiki. Its entries can be incomplete, out of date or wrong, and nothing here is a diagnosis or medical advice. Magnitude is a community rating of how interesting a genotype is, not a risk score.