rs6413420
A SNP in the CYP2E1 gene on chromosome 10. Its most notable genotype is G;G: normal
- Gene
- CYP2E1
- Location
- Chr 10133,527,325 (GRCh38)
- Highest magnitude
- 0.0Typical
- Tested on
- 23andMe, AncestryDNA, FamilyTreeDNA
- Minor allele frequency
- 3%
Genotypes
As shown in 23andMe and AncestryDNA files.
- G;GMost notableGoodnormal
- G;TNot ratedcarrier of one CYP2E1*7_-71G>T allele
- T;TNot ratedCYP2E1*7_-71G>T homozygote
On SNPedia: (G;G), (G;T), (T;T). Magnitude rates how notable a genotype is from 0 to 10, not how risky it is.
Frequency
Share of each genotype in 11 HapMap populations.
- AverageG;G 92% G;T 8% T;T 0%
- European ancestry (Utah)G;G 86% G;T 14% T;T 0%
- Han Chinese (Beijing)G;G 99% G;T 2% T;T 0%
- Japanese (Tokyo)G;G 99% G;T <1% T;T 0%
- Yoruba (Nigeria)G;G 98% G;T 2% T;T 0%
- African ancestry (Southwest US)G;G 97% G;T 4% T;T 0%
- Chinese (Denver)G;G 98% G;T 2% T;T 0%
- Gujarati IndianG;G 80% G;T 20% T;T 0%
- Luhya (Kenya)G;G 97% G;T 3% T;T 0%
- Mexican ancestry (Los Angeles)G;G 95% G;T 5% T;T 0%
- Maasai (Kenya)G;G 85% G;T 15% T;T 0%
- TuscanG;G 83% G;T 17% T;T 0%
Related
Other CYP2E1 SNPs
- rs2070672G;GCYP2E1*7_-352A>G homozygoteWorth knowing
- rs2070676G;GCYP2E1*1B homozygoteWorth knowing
- rs2515641T;TCYP2E1_10463T>C(F421F) homozygoteWorth knowing
- rs915908G;Gcommon in complete genomicsTypical
- rs915909C;CnormalTypical
- rs2031920C;CnormalTypical
- rs2070673A;ACYP2E1*7_-333T>A homozygoteTypical
- rs3813865G;Gcommon in complete genomicsTypical
Notes
From SNPedia
Notes
rs6413420 is a SNP in the CYP2E1 gene. The rs6413420(T) allele defines the CYP2E1*7_-71G>T variant.
Source and license
Adapted from rs6413420 on SNPedia, using a snapshot taken October 16, 2026. SNPedia content is shared under CC BY-NC-SA 3.0 US, and this page is shared under the same license.
SNPedia is a community-edited wiki. Its entries can be incomplete, out of date or wrong, and nothing here is a diagnosis or medical advice. Magnitude is a community rating of how interesting a genotype is, not a risk score.