rs6413432
A SNP in the CYP2E1 gene on chromosome 10. Its most notable genotype is A;A: CYP2E1_marker9 homozygote
- Gene
- CYP2E1
- Location
- Chr 10133,535,040 (GRCh38)
- Highest magnitude
- 0.0Typical
- Tested on
- Not on consumer chips
- Minor allele frequency
- 15%
Genotypes
As shown in 23andMe and AncestryDNA files.
- A;AMost notableNot ratedCYP2E1_marker9 homozygote
- A;TNot ratedcarrier of one CYP2E1_marker9 allele
- T;TNot ratednormal
On SNPedia: (A;A), (A;T), (T;T). Magnitude rates how notable a genotype is from 0 to 10, not how risky it is.
Related
Other CYP2E1 SNPs
- rs2070672G;GCYP2E1*7_-352A>G homozygoteWorth knowing
- rs2070676G;GCYP2E1*1B homozygoteWorth knowing
- rs2515641T;TCYP2E1_10463T>C(F421F) homozygoteWorth knowing
- rs915908G;Gcommon in complete genomicsTypical
- rs915909C;CnormalTypical
- rs2031920C;CnormalTypical
- rs2070673A;ACYP2E1*7_-333T>A homozygoteTypical
- rs3813865G;Gcommon in complete genomicsTypical
Notes
From SNPedia
Show notes, about 130 words
rs6413432 is a SNP in the CYP2E1 gene. The rs6413432(A) allele defines the CYP2E1_marker9 variant, as used in the 2008 study determining the 16 most common CYP2E1 haplotypes world-wide.(see CYP2E1 for details) Dietary phytoestrogen intake is associated with reduced colorectal cancer risk. Genotype and allele frequencies of polymorphic CYP2E1 in the Turkish population. Genotyping panel for assessing response to cancer chemotherapy. Global patterns of variation in allele and haplotype frequencies and linkage disequilibrium across the CYP2E1 gene. Red meat intake, doneness, polymorphisms in genes that encode carcinogen-metabolizing enzymes, and colorectal cancer risk. Genetic variants involved in gallstone formation and capsaicin metabolism, and the risk of gallbladder cancer in Chilean women.
Source and license
Adapted from rs6413432 on SNPedia, using a snapshot taken October 16, 2026. SNPedia content is shared under CC BY-NC-SA 3.0 US, and this page is shared under the same license.
SNPedia is a community-edited wiki. Its entries can be incomplete, out of date or wrong, and nothing here is a diagnosis or medical advice. Magnitude is a community rating of how interesting a genotype is, not a risk score.