rs7195539
A SNP in the FTO gene on chromosome 16. Its most notable genotype is A;A: common genotype
- Gene
- FTO
- Location
- Chr 1653,825,246 (GRCh38)
- Highest magnitude
- 0.0Typical
- Tested on
- 23andMe, AncestryDNA, FamilyTreeDNA
Genotypes
As shown in 23andMe and AncestryDNA files.
On SNPedia: (A;A). Magnitude rates how notable a genotype is from 0 to 10, not how risky it is.
Frequency
Share of each genotype in 11 HapMap populations.
- AverageA;A 78%
- European ancestry (Utah)A;A 92%
- Han Chinese (Beijing)A;A 84%
- Japanese (Tokyo)A;A 74%
- Yoruba (Nigeria)A;A 64%
- African ancestry (Southwest US)A;A 75%
- Chinese (Denver)A;A 84%
- Gujarati IndianA;A 76%
- Luhya (Kenya)A;A 69%
- Mexican ancestry (Los Angeles)A;A 67%
- Maasai (Kenya)A;A 81%
- TuscanA;A 94%
Related
Other FTO SNPs
- rs1421085C;C~1.7x increased obesity riskImportant
- rs1121980A;AModerate increase (2.76x) in risk for obesityImportant
- rs9939609A;Aobesity risk and 1.6x risk for T2DImportant
- rs121918214A;GCarrier of a GDFD mutation (see text)Important
- rs16953002A;A1.32x increased risk of melanoma in those with low BMIMinor
- rs8050136A;A1.4x increased risk for T2D in some populationsMinor
- rs1558902A;AHigher BMI than normalTypical
- rs3751812G;GnormalTypical
Source and license
Adapted from rs7195539 on SNPedia, using a snapshot taken October 16, 2026. SNPedia content is shared under CC BY-NC-SA 3.0 US, and this page is shared under the same license.
SNPedia is a community-edited wiki. Its entries can be incomplete, out of date or wrong, and nothing here is a diagnosis or medical advice. Magnitude is a community rating of how interesting a genotype is, not a risk score.