rs7204609
A SNP in the FTO gene on chromosome 16. Its most notable genotype is T;T: common in complete genomics
- Gene
- FTO
- Location
- Chr 1653,799,693 (GRCh38)
- Highest magnitude
- 0.0Typical
- Tested on
- AncestryDNA
- Minor allele frequency
- 23%
Genotypes
As shown in 23andMe and AncestryDNA files.
On SNPedia: (T;T). Magnitude rates how notable a genotype is from 0 to 10, not how risky it is.
Frequency
Share of each genotype in 11 HapMap populations.
- AverageT;T 54%
- European ancestry (Utah)T;T 97%
- Han Chinese (Beijing)T;T 32%
- Japanese (Tokyo)T;T 32%
- Yoruba (Nigeria)T;T 33%
- African ancestry (Southwest US)T;T 40%
- Chinese (Denver)T;T 39%
- Gujarati IndianT;T 85%
- Luhya (Kenya)T;T 34%
- Mexican ancestry (Los Angeles)T;T 74%
- Maasai (Kenya)T;T 36%
- TuscanT;T 95%
Related
Other FTO SNPs
- rs1421085C;C~1.7x increased obesity riskImportant
- rs1121980A;AModerate increase (2.76x) in risk for obesityImportant
- rs9939609A;Aobesity risk and 1.6x risk for T2DImportant
- rs121918214A;GCarrier of a GDFD mutation (see text)Important
- rs16953002A;A1.32x increased risk of melanoma in those with low BMIMinor
- rs8050136A;A1.4x increased risk for T2D in some populationsMinor
- rs1558902A;AHigher BMI than normalTypical
- rs3751812G;GnormalTypical
Notes
From SNPedia
Notes
Variations in the FTO gene are associated with severe obesity in the Japanese. FTO gene variation and measures of body mass in an African population. Analysis of FTO gene variants with measures of obesity and glucose homeostasis in the IRAS Family Study. Design and evaluation of a treatment programme for Spanish adolescents with overweight and obesity. The EVASYON Study. FTO genetic variation and association with obesity in West Africans and African Americans. A latent variable partial least squares path modeling approach to regional association and polygenic effect with applications to a human obesity study.
Source and license
Adapted from rs7204609 on SNPedia, using a snapshot taken October 16, 2026. SNPedia content is shared under CC BY-NC-SA 3.0 US, and this page is shared under the same license.
SNPedia is a community-edited wiki. Its entries can be incomplete, out of date or wrong, and nothing here is a diagnosis or medical advice. Magnitude is a community rating of how interesting a genotype is, not a risk score.