rs7903146(C;T)

1.4x increased risk for diabetes (and perhaps colon cancer).

Magnitude
2.1Worth knowing
Repute
Bad
Frequency
31%Average of 11 populations
On SNPedia
rs7903146(C;T)
Gene
TCF7L2

Frequency

Share of people with C;T in each HapMap population.

  • African ancestry (Southwest US)50%
  • Yoruba (Nigeria)43%
  • Gujarati Indian42%
  • Tuscan41%
  • Maasai (Kenya)40%
  • Luhya (Kenya)39%
  • Mexican ancestry (Los Angeles)38%
  • European ancestry (Utah)35%
  • Chinese (Denver)7%
  • Japanese (Tokyo)5%
  • Han Chinese (Beijing)5%

Other genotypes of rs7903146

  1. C;CGoodNormal (lower) risk of Type 2 Diabetes and Gestational Diabetes.Worth knowing · 2.062% of people
  2. T;TMost notableBad2x increased risk for Type-2 diabetesImportant · 3.57% of people

All about rs7903146

Notes

From SNPedia

Higher risk for Type 2 Diabetes and Gestational Diabetes. Reduced insulin secretion in the pancreas. This has been confirmed in most races.

Source and license

Adapted from rs7903146(C;T) on SNPedia, using a snapshot taken October 16, 2026. SNPedia content is shared under CC BY-NC-SA 3.0 US, and this page is shared under the same license.

SNPedia is a community-edited wiki. Its entries can be incomplete, out of date or wrong, and nothing here is a diagnosis or medical advice. Magnitude is a community rating of how interesting a genotype is, not a risk score.