rs9383951
A SNP in the ESR1 gene on chromosome 6. Its most notable genotype is G;G: common in complete genomics
- Gene
- ESR1
- Location
- Chr 6151,974,478 (GRCh38)
- Highest magnitude
- 0.0Typical
- Tested on
- AncestryDNA
- Minor allele frequency
- 7%
Genotypes
As shown in 23andMe and AncestryDNA files.
On SNPedia: (G;G). Magnitude rates how notable a genotype is from 0 to 10, not how risky it is.
Frequency
Share of each genotype in 9 HapMap populations.
- AverageG;G 80%
- European ancestry (Utah)G;G 99%
- Han Chinese (Beijing)G;G 83%
- Japanese (Tokyo)G;G 87%
- Yoruba (Nigeria)G;G 75%
- African ancestry (Southwest US)G;G 61%
- Chinese (Denver)G;G 83%
- Gujarati IndianG;G 93%
- Luhya (Kenya)G;G 61%
- Maasai (Kenya)G;G 75%
Related
Other ESR1 SNPs
- rs9340799G;GWomen have 10x risk of Endometriosis, but half the risk of Endometrial Cancer and 0.76x less cognitive impairment.Important
- rs104893956C;TCarrier for an estrogen resistance mutationImportant
- rs121913044A;TCarrier for an estrogen resistance mutationImportant
- rs397509428G;TCarrier for an estrogen resistance mutationImportant
- rs2881766G;TSlightly increased risk for pregnancy-induced hypertensionMinor
- rs2295190T;TSlightly increased risk for ovarian cancer in womenMinor
- rs728524A;Acommon in complete genomicsTypical
- rs2179922A;Amales 1-2cm shorter on averageTypical
Source and license
Adapted from rs9383951 on SNPedia, using a snapshot taken October 16, 2026. SNPedia content is shared under CC BY-NC-SA 3.0 US, and this page is shared under the same license.
SNPedia is a community-edited wiki. Its entries can be incomplete, out of date or wrong, and nothing here is a diagnosis or medical advice. Magnitude is a community rating of how interesting a genotype is, not a risk score.