rs10983755
A SNP in the TLR4 gene on chromosome 9. Its most notable genotype is G;G: common in complete genomics
- Gene
- TLR4
- Location
- Chr 9117,702,392 (GRCh38)
- Highest magnitude
- 0.0Typical
- Tested on
- AncestryDNA
- Minor allele frequency
- 9%
Genotypes
As shown in 23andMe and AncestryDNA files.
On SNPedia: (G;G). Magnitude rates how notable a genotype is from 0 to 10, not how risky it is.
Frequency
Share of each genotype in 10 HapMap populations.
- AverageG;G 82%
- European ancestry (Utah)G;G 94%
- Han Chinese (Beijing)G;G 53%
- Japanese (Tokyo)G;G 58%
- Yoruba (Nigeria)G;G 99%
- African ancestry (Southwest US)G;G 93%
- Chinese (Denver)G;G 51%
- Gujarati IndianG;G 86%
- Mexican ancestry (Los Angeles)G;G 98%
- Maasai (Kenya)G;G 93%
- TuscanG;G 93%
Related
Other TLR4 SNPs
- rs4986790G;Gcomplex; numerous associations reportedWorth knowing
- rs4986791T;Tcomplex; see detailsWorth knowing
- rs1554973C;Cincreased risk for chorionic plate inflammationWorth knowing
- rs10759932C;Cincreased risk for chorionic plate inflammationWorth knowing
- rs1927911G;GnormalTypical
- rs5030719G;Gcommon in complete genomicsTypical
- rs5030729A;Acommon in complete genomicsTypical
- rs11536869A;Acommon genotypeTypical
Notes
From SNPedia
Notes
Genetic variation and haplotype structures of innate immunity genes in eastern India. STAT2*C related genotypes and allele but not TLR4 and CD40 gene polymorphisms are associated with higher susceptibility for asthma.
Source and license
Adapted from rs10983755 on SNPedia, using a snapshot taken October 16, 2026. SNPedia content is shared under CC BY-NC-SA 3.0 US, and this page is shared under the same license.
SNPedia is a community-edited wiki. Its entries can be incomplete, out of date or wrong, and nothing here is a diagnosis or medical advice. Magnitude is a community rating of how interesting a genotype is, not a risk score.