rs2197423
A SNP in the PPARG gene on chromosome 3. Its most notable genotype is G;G.
- Gene
- PPARG
- Location
- Chr 312,350,084 (GRCh38)
- Highest magnitude
- 0.0Typical
- Tested on
- 23andMe, AncestryDNA, FamilyTreeDNA
- Minor allele frequency
- 11%
Genotypes
Plus strand, as in 23andMe and AncestryDNA files.
SNPedia records rs2197423 on the minus strand: (C;C). Magnitude rates how notable a genotype is from 0 to 10, not how risky it is.
Frequency
Share of each genotype in 11 HapMap populations.
- AverageG;G 79%
- European ancestry (Utah)G;G 82%
- Han Chinese (Beijing)G;G 88%
- Japanese (Tokyo)G;G 95%
- Yoruba (Nigeria)G;G 67%
- African ancestry (Southwest US)G;G 63%
- Chinese (Denver)G;G 94%
- Gujarati IndianG;G 83%
- Luhya (Kenya)G;G 69%
- Mexican ancestry (Los Angeles)G;G 83%
- Maasai (Kenya)G;G 56%
- TuscanG;G 86%
Related
Conditions, medicines and genes
Other PPARG SNPs
- rs1801282C;GUnconfirmed higher risk of cardiovascular disease with high saturated fat dietImportant
- rs17036170A;AElevated risk for drug induced liver injury with diclofenacWorth knowing
- rs1899951C;CNo summary available.Typical
- rs3856806C;Ccommon in clinvarTypical
- rs6802898C;CNo summary available.Typical
- rs13306747C;Ccommon in clinvarTypical
- rs17036314C;Crisk of progressing from IGT to T2D; reduced by exerciseTypical
- rs17241090C;CNo summary available.Typical
Notes
From SNPedia
Notes
associated with type-2 diabetes
Source and license
Adapted from rs2197423 on SNPedia, using a snapshot taken October 16, 2026. SNPedia content is shared under CC BY-NC-SA 3.0 US, and this page is shared under the same license.
SNPedia is a community-edited wiki. Its entries can be incomplete, out of date or wrong, and nothing here is a diagnosis or medical advice. Magnitude is a community rating of how interesting a genotype is, not a risk score.