rs2256871

A SNP in the CYP2C9 gene on chromosome 10. Its most notable genotype is G;G: CYP2C9*9 homozygote

Gene
CYP2C9
Location
Chr 1094,949,217 (GRCh38)
Highest magnitude
0.0Typical
Tested on
23andMe, AncestryDNA, FamilyTreeDNA
Minor allele frequency
3%

Genotypes

Plus strand, as in 23andMe and AncestryDNA files.

  1. G;GMost notableNot ratedCYP2C9*9 homozygoteTypical · 0.00% of people
  2. A;GNot ratedcarrier of one CYP2C9*9 alleleTypical · 0.04% of people
  3. A;AGoodnormalTypical · 0.096% of people

SNPedia records rs2256871 on the minus strand: (C;C), (C;T), (T;T). Magnitude rates how notable a genotype is from 0 to 10, not how risky it is.

Frequency

Share of each genotype in 4 HapMap populations.

  • AverageG;G 0% A;G 4% A;A 96%
  • European ancestry (Utah)G;G 0% A;G 2% A;A 99%
  • Han Chinese (Beijing)G;G 0% A;G 0% A;A 100%
  • Japanese (Tokyo)G;G 0% A;G 0% A;A 100%
  • Yoruba (Nigeria)G;G 0% A;G 16% A;A 84%

Notes

From SNPedia

Notes

rs2256871, also known as 752A>G, 10535A>G or H251R, is a SNP in the CYP2C9 gene. The rs2256871(C) allele defines the CYP2C9*9 variant.

Source and license

Adapted from rs2256871 on SNPedia, using a snapshot taken October 16, 2026. SNPedia content is shared under CC BY-NC-SA 3.0 US, and this page is shared under the same license.

SNPedia is a community-edited wiki. Its entries can be incomplete, out of date or wrong, and nothing here is a diagnosis or medical advice. Magnitude is a community rating of how interesting a genotype is, not a risk score.