rs72558188
A SNP in the CYP2C9 gene on chromosome 10. Its most notable genotype is -;-: inactive CYP2C9
- Gene
- CYP2C9
- Location
- Chr 1096,701,979 (GRCh38)
- Highest magnitude
- 4.0Very important
- Tested on
- 23andMe, AncestryDNA
Genotypes
As shown in 23andMe and AncestryDNA files.
- -;-Most notableNot ratedinactive CYP2C9
- -;AGAAATGGAANot ratedcarrier of one CYP2C9*25 allele
- AGAAATGGAA;AGAAATGGAAGoodnormal
On SNPedia: (-;-), (-;AGAAATGGAA), (AGAAATGGAA;AGAAATGGAA). Magnitude rates how notable a genotype is from 0 to 10, not how risky it is.
Related
Conditions, medicines and genes
Other CYP2C9 SNPs
- rs1057909G;GCYP2C9_42612A>G homozygoteVery important
- rs1057910C;CCYP2C9*3 homozygote; average 80% reduction in warfarin metabolism; reduced metabolism of number of other drugsVery important
- rs1057911A;Tcarrier of one CYP2C9_50298A>T alleleImportant
- rs10509680G;TNo summary available.Important
- rs9332131-;-CYP2C9*6 homozygoteWorth knowing
- rs28371685T;TCYP2C9*11 homozygoteWorth knowing
- rs28371686G;GCYP2C9*5 homozygoteWorth knowing
- rs72558189A;ACYP2C9*14 homozygoteWorth knowing
Notes
From SNPedia
Notes
rs72558188, also known as 353_362delAGAAATGGAA or 118Frameshift, is a SNP in the CYP2C9 gene. The rs72558188(-) allele defines the CYP2C9*25 variant, which is inactive.
-;-
CYP2C9*25 homozygote. Likely to influence metabolism of Warfarin and many other medicines.
-;AGAAATGGAA
one non functioning CYP2C9 gene should influence the metabolism of Warfarin and many other medicines.
Source and license
Adapted from rs72558188 on SNPedia, using a snapshot taken October 16, 2026. SNPedia content is shared under CC BY-NC-SA 3.0 US, and this page is shared under the same license.
SNPedia is a community-edited wiki. Its entries can be incomplete, out of date or wrong, and nothing here is a diagnosis or medical advice. Magnitude is a community rating of how interesting a genotype is, not a risk score.