rs3752246
A SNP in the ABCA7 gene on chromosome 19. Its most notable genotype is C;C: common on affy axiom data
- Gene
- ABCA7
- Location
- Chr 191,056,493 (GRCh38)
- Highest magnitude
- 0.0Typical
- Tested on
- AncestryDNA
- Minor allele frequency
- 18%
Genotypes
As shown in 23andMe and AncestryDNA files.
On SNPedia: (C;C). Magnitude rates how notable a genotype is from 0 to 10, not how risky it is.
Frequency
Share of each genotype in 4 HapMap populations.
- AverageC;C 63%
- European ancestry (Utah)C;C 65%
- Han Chinese (Beijing)C;C 59%
- Japanese (Tokyo)C;C 30%
- Yoruba (Nigeria)C;C 100%
Related
Other ABCA7 SNPs
- rs113809142G;Gsomewhat higher risk for AlzheimersImportant
- rs200538373C;Csomewhat higher risk for AlzheimersImportant
- rs72973581A;ASomewhat (0.4x?) lower risk for Alzheimer's, according to one studyWorth knowing
- rs115550680G;GIncreased risk (~2.2x?) of Alzheimer's, observed for African-AmericansWorth knowing
- rs78117248A;Grisk factor for Alzheimer disease (odds ratio ~2x)Worth knowing
- rs3764650G;GLate onset?Typical
- rs4147918A;Acommon genotypeTypical
Source and license
Adapted from rs3752246 on SNPedia, using a snapshot taken October 16, 2026. SNPedia content is shared under CC BY-NC-SA 3.0 US, and this page is shared under the same license.
SNPedia is a community-edited wiki. Its entries can be incomplete, out of date or wrong, and nothing here is a diagnosis or medical advice. Magnitude is a community rating of how interesting a genotype is, not a risk score.