rs3847987
A SNP in the VDR gene on chromosome 12. Its most notable genotype is C;C: common in clinvar
- Gene
- VDR
- Location
- Chr 1247,844,285 (GRCh38)
- Highest magnitude
- 0.0Typical
- Tested on
- 23andMe, AncestryDNA, FamilyTreeDNA
- Minor allele frequency
- 15%
Genotypes
As shown in 23andMe and AncestryDNA files.
On SNPedia: (C;C). Magnitude rates how notable a genotype is from 0 to 10, not how risky it is.
Frequency
Share of each genotype in 11 HapMap populations.
- AverageC;C 75%
- European ancestry (Utah)C;C 78%
- Han Chinese (Beijing)C;C 60%
- Japanese (Tokyo)C;C 60%
- Yoruba (Nigeria)C;C 88%
- African ancestry (Southwest US)C;C 79%
- Chinese (Denver)C;C 54%
- Gujarati IndianC;C 83%
- Luhya (Kenya)C;C 93%
- Mexican ancestry (Los Angeles)C;C 69%
- Maasai (Kenya)C;C 89%
- TuscanC;C 69%
Related
Other VDR SNPs
- rs2107301A;A2.5x higher risk for prostate cancerImportant
- rs1544410T;TIncreased risk of low bone mineral density disordersWorth knowing
- rs731236A;GNo summary available.Typical
- rs739837G;Gcommon in clinvarTypical
- rs2228570A;Acommon in clinvarTypical
- rs4516035C;Cif less milk in teenage females, less bone?Typical
- rs11574085T;Tcommon in complete genomicsTypical
- rs11574129A;Acommon in clinvarTypical
Notes
From SNPedia
Notes
rs3847987 in the vitamin D pathway was associated with the time to onset of COPD. The SNP is a cytosine-to-adenine switch, and men with two copies of the adenine variant were more likely to develop COPD. The hazard ratio was 1.60, with a 95% confidence interval from 1.26 to 2.05, which was significant at P=0.005. news
Source and license
Adapted from rs3847987 on SNPedia, using a snapshot taken October 16, 2026. SNPedia content is shared under CC BY-NC-SA 3.0 US, and this page is shared under the same license.
SNPedia is a community-edited wiki. Its entries can be incomplete, out of date or wrong, and nothing here is a diagnosis or medical advice. Magnitude is a community rating of how interesting a genotype is, not a risk score.