rs731236
A SNP in the VDR gene on chromosome 12. Its most notable genotype is A;G.
- Gene
- VDR
- Location
- Chr 1247,844,974 (GRCh38)
- Highest magnitude
- 0.0Typical
- Tested on
- 23andMe, AncestryDNA, FamilyTreeDNA
- Minor allele frequency
- 26%
Genotypes
Plus strand, as in 23andMe and AncestryDNA files.
SNPedia records rs731236 on the minus strand: (C;T), (T;T). Magnitude rates how notable a genotype is from 0 to 10, not how risky it is.
Frequency
Share of each genotype in 11 HapMap populations.
- AverageA;G 36% A;A 57%
- European ancestry (Utah)A;G 43% A;A 35%
- Han Chinese (Beijing)A;G 6% A;A 94%
- Japanese (Tokyo)A;G 21% A;A 80%
- Yoruba (Nigeria)A;G 46% A;A 49%
- African ancestry (Southwest US)A;G 39% A;A 55%
- Chinese (Denver)A;G 9% A;A 91%
- Gujarati IndianA;G 47% A;A 47%
- Luhya (Kenya)A;G 38% A;A 54%
- Mexican ancestry (Los Angeles)A;G 39% A;A 58%
- Maasai (Kenya)A;G 58% A;A 28%
- TuscanA;G 49% A;A 34%
Related
Conditions, medicines and genes
Other VDR SNPs
- rs2107301A;A2.5x higher risk for prostate cancerImportant
- rs1544410T;TIncreased risk of low bone mineral density disordersWorth knowing
- rs739837G;Gcommon in clinvarTypical
- rs2228570A;Acommon in clinvarTypical
- rs3847987C;Ccommon in clinvarTypical
- rs4516035C;Cif less milk in teenage females, less bone?Typical
- rs11574085T;Tcommon in complete genomicsTypical
- rs11574129A;Acommon in clinvarTypical
Notes
From SNPedia
Notes
rs731236 protection from breast cancer (OR=0.80, 95%CI=0.64-0.99; p= 0.047)
Source and license
Adapted from rs731236 on SNPedia, using a snapshot taken October 16, 2026. SNPedia content is shared under CC BY-NC-SA 3.0 US, and this page is shared under the same license.
SNPedia is a community-edited wiki. Its entries can be incomplete, out of date or wrong, and nothing here is a diagnosis or medical advice. Magnitude is a community rating of how interesting a genotype is, not a risk score.