rs739837
A SNP in the VDR gene on chromosome 12. Its most notable genotype is G;G: common in clinvar
- Gene
- VDR
- Location
- Chr 1247,844,438 (GRCh38)
- Highest magnitude
- 0.0Typical
- Tested on
- 23andMe, AncestryDNA
- Minor allele frequency
- 48%
Genotypes
As shown in 23andMe and AncestryDNA files.
On SNPedia: (G;G). Magnitude rates how notable a genotype is from 0 to 10, not how risky it is.
Frequency
Share of each genotype in 11 HapMap populations.
- AverageG;G 28%
- European ancestry (Utah)G;G 23%
- Han Chinese (Beijing)G;G 54%
- Japanese (Tokyo)G;G 45%
- Yoruba (Nigeria)G;G 21%
- African ancestry (Southwest US)G;G 18%
- Chinese (Denver)G;G 47%
- Gujarati IndianG;G 22%
- Luhya (Kenya)G;G 14%
- Mexican ancestry (Los Angeles)G;G 31%
- Maasai (Kenya)G;G 14%
- TuscanG;G 19%
Related
Other VDR SNPs
- rs2107301A;A2.5x higher risk for prostate cancerImportant
- rs1544410T;TIncreased risk of low bone mineral density disordersWorth knowing
- rs731236A;GNo summary available.Typical
- rs2228570A;Acommon in clinvarTypical
- rs3847987C;Ccommon in clinvarTypical
- rs4516035C;Cif less milk in teenage females, less bone?Typical
- rs11574085T;Tcommon in complete genomicsTypical
- rs11574129A;Acommon in clinvarTypical
Notes
From SNPedia
Notes
rs739837 fair skin (OR=1.31, p=0.048) Vitamin D pathway gene variants and prostate cancer risk. Pharmacogenetic risk factors for altered bone mineral density and body composition in pediatric acute lymphoblastic leukemia.
Source and license
Adapted from rs739837 on SNPedia, using a snapshot taken October 16, 2026. SNPedia content is shared under CC BY-NC-SA 3.0 US, and this page is shared under the same license.
SNPedia is a community-edited wiki. Its entries can be incomplete, out of date or wrong, and nothing here is a diagnosis or medical advice. Magnitude is a community rating of how interesting a genotype is, not a risk score.