rs4917639
A SNP in the CYP2C9 gene on chromosome 10. Its most notable genotype is A;A: common in clinvar
- Gene
- CYP2C9
- Location
- Chr 1094,965,778 (GRCh38)
- Highest magnitude
- 0.0Typical
- Tested on
- 23andMe, AncestryDNA, FamilyTreeDNA
- Minor allele frequency
- 17%
Genotypes
As shown in 23andMe and AncestryDNA files.
On SNPedia: (A;A). Magnitude rates how notable a genotype is from 0 to 10, not how risky it is.
Frequency
Share of each genotype in 11 HapMap populations.
- AverageA;A 69%
- European ancestry (Utah)A;A 64%
- Han Chinese (Beijing)A;A 85%
- Japanese (Tokyo)A;A 82%
- Yoruba (Nigeria)A;A 68%
- African ancestry (Southwest US)A;A 63%
- Chinese (Denver)A;A 84%
- Gujarati IndianA;A 65%
- Luhya (Kenya)A;A 57%
- Mexican ancestry (Los Angeles)A;A 67%
- Maasai (Kenya)A;A 66%
- TuscanA;A 59%
Related
Other CYP2C9 SNPs
- rs1057909G;GCYP2C9_42612A>G homozygoteVery important
- rs1057910C;CCYP2C9*3 homozygote; average 80% reduction in warfarin metabolism; reduced metabolism of number of other drugsVery important
- rs72558188-;-inactive CYP2C9Very important
- rs1057911A;Tcarrier of one CYP2C9_50298A>T alleleImportant
- rs10509680G;TNo summary available.Important
- rs9332131-;-CYP2C9*6 homozygoteWorth knowing
- rs28371685T;TCYP2C9*11 homozygoteWorth knowing
- rs28371686G;GCYP2C9*5 homozygoteWorth knowing
Source and license
Adapted from rs4917639 on SNPedia, using a snapshot taken October 16, 2026. SNPedia content is shared under CC BY-NC-SA 3.0 US, and this page is shared under the same license.
SNPedia is a community-edited wiki. Its entries can be incomplete, out of date or wrong, and nothing here is a diagnosis or medical advice. Magnitude is a community rating of how interesting a genotype is, not a risk score.