rs9332239
A SNP in the CYP2C9 gene on chromosome 10. Its most notable genotype is C;C: normal
- Gene
- CYP2C9
- Location
- Chr 1094,989,020 (GRCh38)
- Highest magnitude
- 0.0Typical
- Tested on
- 23andMe, AncestryDNA
- Minor allele frequency
- <1%
Genotypes
As shown in 23andMe and AncestryDNA files.
- C;CMost notableGoodnormal
- C;TNot ratedcarrier of one CYP2C9*12 allele
- T;TNot ratedCYP2C9*12 homozygote
On SNPedia: (C;C), (C;T), (T;T). Magnitude rates how notable a genotype is from 0 to 10, not how risky it is.
Frequency
Share of each genotype in 4 HapMap populations.
- AverageC;C 100% C;T 0% T;T 0%
- European ancestry (Utah)C;C 100% C;T 0% T;T 0%
- Han Chinese (Beijing)C;C 100% C;T 0% T;T 0%
- Japanese (Tokyo)C;C 100% C;T 0% T;T 0%
- Yoruba (Nigeria)C;C 100% C;T 0% T;T 0%
Related
Other CYP2C9 SNPs
- rs1057909G;GCYP2C9_42612A>G homozygoteVery important
- rs1057910C;CCYP2C9*3 homozygote; average 80% reduction in warfarin metabolism; reduced metabolism of number of other drugsVery important
- rs72558188-;-inactive CYP2C9Very important
- rs1057911A;Tcarrier of one CYP2C9_50298A>T alleleImportant
- rs10509680G;TNo summary available.Important
- rs9332131-;-CYP2C9*6 homozygoteWorth knowing
- rs28371685T;TCYP2C9*11 homozygoteWorth knowing
- rs28371686G;GCYP2C9*5 homozygoteWorth knowing
Genosets
- Gs162CYP2C9 Poor MetabolizersImportant
- Gs161CYP2C9 Intermediate MetabolizersWorth knowing
- Gs160CYP2C9 Extensive MetabolizersMinor
Genosets combine several genotypes. Twofold checks them in your report.
Notes
From SNPedia
Notes
rs9332239, also known as 1465C>T, 50338C>T or P489S, is a SNP in the CYP2C9 gene. The rs9332239(T) allele defines the CYP2C9*12 variant. According to a 23andMe discussion This is one of the SNPs which were re-analyzed April 2009. Customers with older data may wish to redownload. SNPs effected rs4420638, rs34276300, rs3091244, rs34601266, rs2033003, rs7900194, rs9332239, rs28371685, rs1229984, and rs28399504.
Source and license
Adapted from rs9332239 on SNPedia, using a snapshot taken October 16, 2026. SNPedia content is shared under CC BY-NC-SA 3.0 US, and this page is shared under the same license.
SNPedia is a community-edited wiki. Its entries can be incomplete, out of date or wrong, and nothing here is a diagnosis or medical advice. Magnitude is a community rating of how interesting a genotype is, not a risk score.