rs1108580
A SNP in the DBH gene on chromosome 9. Its most notable genotype is A;A: common in clinvar
- Gene
- DBH
- Location
- Chr 9133,639,992 (GRCh38)
- Highest magnitude
- 0.0Typical
- Tested on
- 23andMe, AncestryDNA, FamilyTreeDNA
- Minor allele frequency
- 44%
Genotypes
As shown in 23andMe and AncestryDNA files.
On SNPedia: (A;A). Magnitude rates how notable a genotype is from 0 to 10, not how risky it is.
Frequency
Share of each genotype in 11 HapMap populations.
- AverageA;A 36%
- European ancestry (Utah)A;A 21%
- Han Chinese (Beijing)A;A 70%
- Japanese (Tokyo)A;A 71%
- Yoruba (Nigeria)A;A 10%
- African ancestry (Southwest US)A;A 9%
- Chinese (Denver)A;A 84%
- Gujarati IndianA;A 39%
- Luhya (Kenya)A;A 7%
- Mexican ancestry (Los Angeles)A;A 38%
- Maasai (Kenya)A;A 16%
- TuscanA;A 27%
Related
Other DBH SNPs
- rs2007153T;Tdecreased risk of schizophrenia in limited studyMinor
- rs2283123C;Cnormal risk of schizophrenia in limited studyMinor
- rs4531G;Gcommon on affy axiom dataTypical
- rs5320G;Gcommon in complete genomicsTypical
- rs6271C;Ccommon in clinvarTypical
- rs77905A;Acommon in clinvarTypical
- rs129882C;Ccommon in clinvarTypical
- rs1611115C;CnormalTypical
Genosets
- Gs291Lower heart attack risk than averageImportant
- Gs295Lower heart attack risk than averageWorth knowing
- Gs296Lower heart attack risk than averageWorth knowing
- Gs297Lower heart attack risk than averageWorth knowing
Genosets combine several genotypes. Twofold checks them in your report.
Source and license
Adapted from rs1108580 on SNPedia, using a snapshot taken October 16, 2026. SNPedia content is shared under CC BY-NC-SA 3.0 US, and this page is shared under the same license.
SNPedia is a community-edited wiki. Its entries can be incomplete, out of date or wrong, and nothing here is a diagnosis or medical advice. Magnitude is a community rating of how interesting a genotype is, not a risk score.