rs77905
A SNP in the DBH gene on chromosome 9. Its most notable genotype is A;A: common in clinvar
- Gene
- DBH
- Location
- Chr 9133,652,975 (GRCh38)
- Highest magnitude
- 0.0Typical
- Tested on
- 23andMe, AncestryDNA, FamilyTreeDNA
- Minor allele frequency
- 35%
Genotypes
Plus strand, as in 23andMe and AncestryDNA files.
SNPedia records rs77905 on the minus strand: (T;T). Magnitude rates how notable a genotype is from 0 to 10, not how risky it is.
Frequency
Share of each genotype in 11 HapMap populations.
- AverageA;A 17%
- European ancestry (Utah)A;A 24%
- Han Chinese (Beijing)A;A 0%
- Japanese (Tokyo)A;A 3%
- Yoruba (Nigeria)A;A 16%
- African ancestry (Southwest US)A;A 23%
- Chinese (Denver)A;A 3%
- Gujarati IndianA;A 28%
- Luhya (Kenya)A;A 27%
- Mexican ancestry (Los Angeles)A;A 16%
- Maasai (Kenya)A;A 26%
- TuscanA;A 18%
Related
Other DBH SNPs
- rs2007153T;Tdecreased risk of schizophrenia in limited studyMinor
- rs2283123C;Cnormal risk of schizophrenia in limited studyMinor
- rs4531G;Gcommon on affy axiom dataTypical
- rs5320G;Gcommon in complete genomicsTypical
- rs6271C;Ccommon in clinvarTypical
- rs129882C;Ccommon in clinvarTypical
- rs1108580A;Acommon in clinvarTypical
- rs1611115C;CnormalTypical
Notes
From SNPedia
Notes
Genetic variation in the dopamine pathway and smoking cessation.
Source and license
Adapted from rs77905 on SNPedia, using a snapshot taken October 16, 2026. SNPedia content is shared under CC BY-NC-SA 3.0 US, and this page is shared under the same license.
SNPedia is a community-edited wiki. Its entries can be incomplete, out of date or wrong, and nothing here is a diagnosis or medical advice. Magnitude is a community rating of how interesting a genotype is, not a risk score.