rs4531
A SNP in the DBH gene on chromosome 9. Its most notable genotype is G;G: common on affy axiom data
- Gene
- DBH
- Location
- Chr 9133,644,248 (GRCh38)
- Highest magnitude
- 0.0Typical
- Tested on
- 23andMe, AncestryDNA, FamilyTreeDNA
- Minor allele frequency
- 6%
Genotypes
As shown in 23andMe and AncestryDNA files.
On SNPedia: (G;G). Magnitude rates how notable a genotype is from 0 to 10, not how risky it is.
Frequency
Share of each genotype in 9 HapMap populations.
- AverageG;G 81%
- European ancestry (Utah)G;G 89%
- Japanese (Tokyo)G;G 98%
- Yoruba (Nigeria)G;G 79%
- African ancestry (Southwest US)G;G 70%
- Gujarati IndianG;G 83%
- Luhya (Kenya)G;G 68%
- Mexican ancestry (Los Angeles)G;G 88%
- Maasai (Kenya)G;G 69%
- TuscanG;G 86%
Related
Other DBH SNPs
- rs2007153T;Tdecreased risk of schizophrenia in limited studyMinor
- rs2283123C;Cnormal risk of schizophrenia in limited studyMinor
- rs5320G;Gcommon in complete genomicsTypical
- rs6271C;Ccommon in clinvarTypical
- rs77905A;Acommon in clinvarTypical
- rs129882C;Ccommon in clinvarTypical
- rs1108580A;Acommon in clinvarTypical
- rs1611115C;CnormalTypical
Notes
From SNPedia
Notes
Cholinergic nicotinic receptor genes implicated in a nicotine dependence association study targeting 348 candidate genes with 3713 SNPs.
Source and license
Adapted from rs4531 on SNPedia, using a snapshot taken October 16, 2026. SNPedia content is shared under CC BY-NC-SA 3.0 US, and this page is shared under the same license.
SNPedia is a community-edited wiki. Its entries can be incomplete, out of date or wrong, and nothing here is a diagnosis or medical advice. Magnitude is a community rating of how interesting a genotype is, not a risk score.