rs2007153
A SNP in the DBH gene on chromosome 9. Its most notable genotype is T;T: decreased risk of schizophrenia in limited study
- Gene
- DBH
- Location
- Chr 9133,638,697 (GRCh38)
- Highest magnitude
- 1.5Minor
- Tested on
- 23andMe, AncestryDNA, FamilyTreeDNA
- Minor allele frequency
- 39%
Genotypes
Plus strand, as in 23andMe and AncestryDNA files.
- T;TMost notableGooddecreased risk of schizophrenia in limited study
- C;TNot ratednormal risk of schizophrenia in limited study
- C;CBadincreased risk of schizophrenia in limited study
SNPedia records rs2007153 on the minus strand: (A;A), (A;G), (G;G). Magnitude rates how notable a genotype is from 0 to 10, not how risky it is.
Frequency
Share of each genotype in 11 HapMap populations.
- AverageT;T 18% C;T 43% C;C 39%
- European ancestry (Utah)T;T 17% C;T 40% C;C 43%
- Han Chinese (Beijing)T;T 18% C;T 40% C;C 42%
- Japanese (Tokyo)T;T 10% C;T 45% C;C 45%
- Yoruba (Nigeria)T;T 28% C;T 49% C;C 23%
- African ancestry (Southwest US)T;T 19% C;T 46% C;C 35%
- Chinese (Denver)T;T 10% C;T 34% C;C 56%
- Gujarati IndianT;T 19% C;T 48% C;C 34%
- Luhya (Kenya)T;T 17% C;T 46% C;C 36%
- Mexican ancestry (Los Angeles)T;T 22% C;T 41% C;C 36%
- Maasai (Kenya)T;T 18% C;T 42% C;C 40%
- TuscanT;T 15% C;T 44% C;C 41%
Related
Conditions, medicines and genes
Other DBH SNPs
- rs2283123C;Cnormal risk of schizophrenia in limited studyMinor
- rs4531G;Gcommon on affy axiom dataTypical
- rs5320G;Gcommon in complete genomicsTypical
- rs6271C;Ccommon in clinvarTypical
- rs77905A;Acommon in clinvarTypical
- rs129882C;Ccommon in clinvarTypical
- rs1108580A;Acommon in clinvarTypical
- rs1611115C;CnormalTypical
Notes
From SNPedia
Notes
Associated with schizophrenia in a study of Croatians. Due to the limited number and diversity of the studied population, more study is needed to confirm any link. The G allele was associated with an increased risk of schizophrenia.
Source and license
Adapted from rs2007153 on SNPedia, using a snapshot taken October 16, 2026. SNPedia content is shared under CC BY-NC-SA 3.0 US, and this page is shared under the same license.
SNPedia is a community-edited wiki. Its entries can be incomplete, out of date or wrong, and nothing here is a diagnosis or medical advice. Magnitude is a community rating of how interesting a genotype is, not a risk score.