rs12938245
A SNP in the MAPT gene on chromosome 17. Its most notable genotype is C;C: common in complete genomics
- Gene
- MAPT
- Location
- Chr 1745,983,243 (GRCh38)
- Highest magnitude
- 0.0Typical
- Tested on
- 23andMe
Genotypes
As shown in 23andMe and AncestryDNA files.
On SNPedia: (C;C). Magnitude rates how notable a genotype is from 0 to 10, not how risky it is.
Frequency
Share of each genotype in 4 HapMap populations.
- AverageC;C 100%
- European ancestry (Utah)C;C 100%
- Han Chinese (Beijing)C;C 100%
- Japanese (Tokyo)C;C 100%
- Yoruba (Nigeria)C;C 100%
Related
Other MAPT SNPs
- rs63750424C;TFrontotemporal dementia (predicted)Very important
- rs8070723G;G~0.05x (thus greatly) reduced risk for developing progressive supranuclear palsyWorth knowing
- rs143624519A;Asome increase in risk for neurodegenerative disordersWorth knowing
- rs1800547A;AMAPT H1/H1 diplotypeMinor
- rs7521A;Acommon in clinvarTypical
- rs9468T;Tcommon in clinvarTypical
- rs242557A;GnormalTypical
- rs1052553A;Acommon in clinvarTypical
Source and license
Adapted from rs12938245 on SNPedia, using a snapshot taken October 16, 2026. SNPedia content is shared under CC BY-NC-SA 3.0 US, and this page is shared under the same license.
SNPedia is a community-edited wiki. Its entries can be incomplete, out of date or wrong, and nothing here is a diagnosis or medical advice. Magnitude is a community rating of how interesting a genotype is, not a risk score.